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If your PSA level is high, you might need further tests to look for prostate cancer (see ‘If screening tests results aren’t normal’, below). If the PSA is more than 10, the chance of having prostate cancer is over 50%.Men with a PSA level between 4 and 10 (often called the “borderline range”) have about a 1 in 4 chance of having prostate cancer.
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About 15% of men with a PSA below 4 will have prostate cancer if a biopsy is done. Still, a level below 4 is not a guarantee that a man doesn’t have cancer. When prostate cancer develops, the PSA level often goes above 4.
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Many doctors use a PSA cutoff point of 4 ng/mL or higher when deciding if a man might need further testing, while others might recommend it starting at a lower level, such as 2.5 or 3. The chance of having prostate cancer goes up as the PSA level goes up, but there is no set cutoff point that can tell for sure if a man does or doesn’t have prostate cancer. The PSA level in blood is measured in units called nanograms per milliliter (ng/mL). PSA is mostly found in semen, but a small amount is also found in blood. Prostate-specific antigen (PSA) is a protein made by cells in the prostate gland (both normal cells and cancer cells). Prostate-specific antigen (PSA) blood test If the result of one of these tests is abnormal, you will probably need a prostate biopsy (discussed below) to know for sure if you have cancer. But these tests can’t tell for sure if you have cancer. The screening tests discussed here are used to look for possible signs of prostate cancer. Still, after discussing the pros and cons of screening with their doctors, some men might reasonably choose to be screened. It’s not clear, however, if the benefits of prostate cancer screening outweigh the risks for most men. Screening is testing to find cancer in people before they have symptoms.
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